ea0095p10 | Bone | BSPED2023
Bartlett Tabitha
, Tang Jonathan C Y
, Dunn Rachel
, Subramanian Sharan
, Fraser William D
, Webb Emma
Background: Zoledronate is a nitrogen-containing bisphosphonate (BP) recognised for its antiresorptive potency. The pharmacokinetic/pharmacodynamic of zoledronate remains unclear. Although adverse events from overuse of BP is rare, there have been reports of over-treatment resulting in pathophysiological consequences. The current administration regimen is not tailored to the individuals therapeutic response to zoledronate. Quantifying post-dose serum con...